The first CF rat model, CFTR tm1sage (termed CFTR-/- or KO), was designed in collaboration with SAGE (now Horizon Discovery) and subsequently characterized at UAB and distributed to the CF community.
The CFTR Protein Distribution Core offers high-quality, full-length recombinant cystic fibrosis transmembrane conductance regulator (CFTR) proteins expressed in and purified from mammalian cells. Wild ...
(CFTR) gene. There are around 700 known variants that cause CF, but current treatments address only a few, and none offer a cure. "Therapeutics for cystic fibrosis have hit a plateau, demanding ...
Get Instant Summarized Text (Gist) An inhalable gene therapy, BI 3720931, is being trialed in Europe to treat cystic fibrosis (CF) by inserting a functional CFTR gene into airway epithelial cells ...
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