Early in his studies using budding yeast as a model organism ... a process considered to increase either exponentially or at a constant rate during the yeast cell cycle. The team engineered yeast to ...

budding yeast; visualized with the nuclear DNA stain DAPI (4',6-diamidino-2-phenylindole) to highlight the nucleus. The Domino and Clock Models of Cell Cycle Regulation Different models of cell ...

The irreversibility of cell-cycle transitions is commonly thought ... is initiated by Cdk1–CycB complexes in yeasts (Cdk1–Clb5,6 in budding yeast; Cdk1–Cig2 in fission yeast).

In this regard, we focus on a conserved multiprotein complex that includes Mre11, Rad50, and Nbs1 in mammals or Xrs2 in the budding yeast S. cerevisiae ... that participates in the activation of cell ...