Epigenetic silencing is one way to turn genes off, and it can contribute to differential expression. Silencing might also explain, in part, why genetic twins are not phenotypically identical.

CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

Long-term epigenetic silencing of particular genes could allow them to accumulate genetic mutations and develop new functions over time. There is some correlational evidence that duplicated ...

Mar. 28, 2024 — A research consortium provides evidence that social behavior and social status are reflected at the molecular level of gene activation (epigenome) in ... New Study Reveals ...

The discovery is the first time that epigenetic silencing, the "switching off" of an otherwise intact gene, has been recognized as the cause for a skin disease. Porokeratosis is a skin disease ...

A research team led by Prof. Cao Xiaofeng at the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences (CAS) has uncovered the cooperative roles of photoreceptors, ...

Moreover, research suggests that even these few remaining active transposons are inhibited from jumping in a variety of ways that go beyond epigenetic silencing. The ability of transposons to ...

As a result, the researchers postulated that an epigenetic mechanism that affected whether or not particular genes could be transcribed may be the culprit. They performed RNA sequencing to look at ...

For decades, scientists thought that vertebrates had only one type of epigenetic modification on DNA called cytosine ...

ELXR offers a promising epigenetic editing approach to treat ... enabling therapeutic gene silencing with improved potency and safety About Scribe Therapeutics Scribe Therapeutics is ...

The Cancer Epigenetics Lab (CEL) hosts two independent groups. Karim Malik’s group currently focuses on (i) delineating cellular functions in development and cancer of protocadherins (recently shown ...

"This unique epigenetic landscape may be linked to Spirodela's reproductive strategy, which relies on rapid clonal propagation." The team's findings suggest Spirodela focuses on silencing potentia ...