In addition, exosome delivery systems struggle with preserving bioactivity and maintaining adaptable miRNA cargoes throughout the entire release period, limiting their effectiveness at different ...

Conclusion: The significant difference in total exosome and miRNA levels between lung cancer patients and controls, and the similarity between the circulating exosomal miRNA and the tumor-derived ...

The following is a summary of “Study on the diagnostic role of exosome-derived miRNAs in postoperative septic shock and ...

Comparing exosomes derived from normal cells to those derived from breast cancer cells, Kalluri’s team found the proteins responsible for chopping up miRNA precursors into their mature form present ...

Researchers have found that Sr pretreatment not only increases the production of SMSC-derived exosomes but also optimizes their miRNA profile, enriching them with beneficial miRNAs while reducing ...

Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA ...

Their study investigates how pretreating synovial mesenchymal stem cells (SMSCs) with strontium (Sr) enhances exosome production and miRNA selectively loading, leading to improved therapeutic results ...

Further, through their cargo-carrying capacity, exosomes facilitate the spread of proteins, lipids, mRNA, miRNA, and DNA, which can contribute to their general therapeutic effects. Beyond their ...

microRNA detection in very dilute samples (e.g., urine, CSF) can be boosted by first isolating exosomes in the sample and then profiling microRNAs contained in these extracellular vesicles. The gold ...

A recently published study by the the Western Ontario Registry for Early OA (WOREO) Knee Study team suggests that while synovitis increases in OA, the exhaustion and dysfunction of immune-regulatory ...

Their study investigates how pretreating synovial mesenchymal stem cells (SMSCs) with strontium (Sr) enhances exosome production and miRNA selectively loading, leading to improved therapeutic ...