Gene therapy protects against motor neuron disease in rats
The mutation is in the Trk-fused gene, which typically facilitates the transportation of proteins within nerve cells called ...
Healthline14d
BCR-ABL1 Genetic Testing for the Diagnosis and Treatment of Leukemia
When this occurs, the ABL1 gene on chromosome 9 fuses with the BCR gene on chromosome 22, creating a new fused gene. The BCR-ABL1 oncogene codes for a protein that causes cells to grow and divide ...
Nature5y
Mitochondrial Fusion and Division
Researchers have identified many gene products that control mitochondrial fusion and division. Three central players are (1) mitofusins (outer mitochondrial membrane fusion), (2) OPA1/Mgm1 (inner ...
Nature2mon
Prediction of protein interactions: metabolic enzymes are frequently involved in gene fusion
We have investigated the prediction of protein interactions through the analysis of domain fusion to assess whether metabolic enzymes have a higher participation in gene-fusion events compared ...