Melinoë's chances of reaching any of the aforementioned biome bosses is greatly increased by using Hades 2 Arcana cards effectively. Another key factor will be the gear you're working with.

Square Enix/Wizards of the Coast Magic: The Gathering/Final Fantasy Summon Shive card (back) Wizards of the Coast/Square Enix Magic: The Gathering/Final Fantasy Hades card Square Enix/Wizards of ...

Arcana Cards have also been given a makeover with some gorgeous new art. Some even have reworked or tweaked effects, so make sure you check them out carefully the next time you jump into Hades 2.