Single-cell analysis revealed the molecular triggers that drive stem cells to become cancerous, which may help inform ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), ...

The HIPPO pathway controls organ size by regulating cell proliferation and apoptosis, acting through its core components MST1/2, LATS1/2, and downstream effectors YAP and TAZ. In the liver ...

S-969, a first-in-class small molecule targeting a key kinase on the Hippo-YAP axis, has demonstrated promising potential in addressing debilitating conditions such as Duchenne muscular dystrophy ...