It determines the number of low-density lipoprotein (LDL) receptors in the body. These receptors then regulate how much LDL cholesterol (sometimes called “bad” cholesterol) goes into our ...

Once processed by LPL, the VLDL becomes a VLDL remnant. The majority of the VLDL remnants are taken up by the liver via the LDL receptor, and the remaining remnant particles become IDL ...

Office coffee doesn't pretend to be the crème de la crème of brews, but new research suggests your common room’s cup of joe ...

AstraZeneca’s AZD0780 is an investigational oral medication that was developed to lower low-density lipoprotein cholesterol ...

A cholesterol receptor protein called LDLR appears to be a key driver of neurotoxicity in sporadic ALS, per new research ...

By Vijay Kumar Malesu Study deciphers the molecular handshake between LDL receptors and apoB100, shedding light on cholesterol metabolism and its role in cardiovascular disease. Study: Structure of ...

Familial hypercholesterolemia results from gene mutations approximately halving the number of functional LDL receptors in heterozygotes and a greater lack in homozygotes. Reduced receptor-mediated ...

which inactivate LDL receptors on target tissues. [Grundy 2018;10b-c] The triglyceride-lowering drugs — fibrates and niacin— also have a mild LDL-C-lowering effect. [Grundy 2018;10c] Bempedoic ...

Vect-Horus has demonstrated how small peptides that target the low-density lipoprotein (LDL) receptor can be coupled with drugs and transported across the BBB 1. More recently, the company has ...

LDL is often called “bad” cholesterol because when it accumulates in the blood, it can form plaque in the arteries, a ...

A greater reduction LDL-C was seen for combo therapy; reductions also seen in all-cause mortality, major adverse CV events, stroke incidence. HealthDay News — Combination lipid-lowering therapy ...