"Consenting family members should be offered a standard ... "The justly celebrated unraveling of the LDL receptor pathway ...

Familial hypercholesterolemia results from gene mutations approximately halving the number of functional LDL receptors in heterozygotes and a greater lack in homozygotes. Reduced receptor-mediated ...

Once processed by LPL, the VLDL becomes a VLDL remnant. The majority of the VLDL remnants are taken up by the liver via the LDL receptor, and the remaining remnant particles become IDL ...

A cholesterol receptor protein called LDLR appears to be a key driver of neurotoxicity in sporadic ALS, per new research ...

The three key mutations are in the gene for the LDL cholesterol receptor that is supposed to ... may have FH based on high cholesterol and a family history of early heart disease or heart attacks ...