Oil droplet formation: Oil (yellow) accumulates between the layers of the membrane that forms the endoplasmic reticulum (ER)—a network of membranes within the cytoplasm of plant cells.

In human cells, lipid droplets (LDs) predominantly contain either cholesteryl esters or triacylglycerols. This article ...

Lipid accumulation in tumor cells and nearby immune cells promotes immune suppression and therapy resistance in ...

A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop ...

Seipin forms a flexible cage at lipid droplet formation sites. Nat Struct Mol Biol. 2022 Feb 24. doi: 10.1038/s41594-021-00718-y. Online ahead of print. Mejhert N, Gabriel KR, Frendo-Cumbo S, Krahmer ...

Researchers found they could reverse therapy resistance and the immunosuppressive microenvironment by disrupting lipid droplet formation. Blocking dietary intake of Omega-6 fatty acids also ...

A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop resistance to therapy.

Researchers say they are exploring therapeutic options to block fatty acid accumulation and immunosuppressive signals between ...