Using a novel quantitative chemoproteomic strategy, a research group led by Prof. Wang Chu from the College of Chemistry and ...

The research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University ...

The microtubule-associated protein XMAP215 promotes microtubule growth, but how this occurs has been unclear. To address this question, Gary Brouhard et al. developed a single-molecule ...

Specifically, tau fragments containing the microtubule binding region and its adjacent C-terminal sequence wreaked havoc on synaptic plasticity when injected into rat brains. Scientists led by Michael ...

Akhmanova and colleagues have identified an interaction between the ER membrane resident, stromal interaction molecule 1 (STIM1), and the microtubule plus-end-binding protein EB1, which is ...

The research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University published a research article ...

HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.

The motor domain contains the catalytic site for ATP hydrolysis and the actin or microtubule-binding site. The neck region acts as a lever arm, amplifying the small conformational changes generated by ...

Using a novel quantitative chemoproteomic strategy, the team uncovered a protective role of dopamine (DA) in regulating the function of the microtubule-associated protein Tau. This discovery ...