Three mammalian class II isoforms have been identified: the ubiquitously expressed PI3K-C2α and PI3K-C2β, and liver-specific PI3K-C2γ. Class III PI3Ks are heterodimeric enzymes consisting of ...

inhibitor with predominant inhibitory activity against PI3K-α and PI3K-δ isoforms, which the FDA will review in relapsed or refractory follicular lymphoma patients who have received at least ...

Infinity Pharmaceuticals has gained access to Intellikine's portfolio of phosphoinositide 3-kinase-δ (PI3Kδ) and PI3Kγ inhibitors for inflammation and oncology indications through an exclusive ...