The polymer, called polyethylene glycol or PEG, works by "fusing" the membranes of damaged nerve cells, and it can be applied up to eight hours after the injury without adversely affecting the patient ...
For the past 30 years, scientists have improved various chemistries to build PEG polymers and attach them to a polypeptide drug of choice. Among the first pegylated drugs approved by the FDA in ...
Phys.org on MSN5d
Molecular motors in action: visualizing alpha-cyclodextrin movement along polymer chainsImagine a microscopic locomotive moving back and forth along a track, propelling itself without any external force. At the molecular level, this concept forms the foundation of molecular motors -- ...
PEG-Naloxol (NKTR-118) in Phase II clinical trials. Clinical benefit has already been demonstrated with polymer–drug conjugates bearing classical chemotherapeutic agents. The future of cancer ...
Fast-scanning atomic force microscopy imaging of the molecule at two different time points shows positional shifts along the polymer chain on the left. On the right, the molecular structure of PEG ...
Recent studies have already reported the use of polymer conjugation techniques with ... Oxidized dextran; PEG: Poly(ethylene glycol); PGA: Poly-L-glutamic acid; PTX: Paclitaxel.
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