Therefore, the second rule in DNA replication is that DNA unwinding and DNA synthesis have to be coordinated ... or outside of S phase, it will always trigger the checkpoint surveillance system ...

However, the conditions for DNA synthesis are rarely ideal ... At the same time, in S-phase, cells need to synthesize new histone proteins which will also be deposited to newly replicated DNA.

The effect of saccharin on the microbiome has received much attention, but its impact on pathogenic bacterial species is less ...