A polymorphism in the serotonin transporter (SERT) gene has been linked to increased susceptibility to PAH, although this polymorphism alone does not appear sufficient to mediate PAH. Emerging ...

Certain brain cells make serotonin and release it into the synapses so it can act on other brain cells. A protein called serotonin transporter (SERT) moves serotonin from a synapse back into the cell ...

One goal of our research is to enhance our understanding of how drugs of abuse, antidepressants, and other small molecules interact with and modulate the function of monoamine transporters (MATs), ...

are drugs that prolong the presence, and thus activity, of serotonin in neural synapses, and are used in the treatment of depression, anxiety and other related disorders. They work by binding and ...