Poorly differentiated, spindle cell malignancies, on sun damaged skin frequently pose a diagnostic challenge for pathologists. The vast majority of these neoplasms ultimately are diagnosed as ...

Being immortal, mitotically competent and located in tissues in which tumours appear, stem cells are likely candidates to initiate tumor growth ... Proper spindle alignment is key for the correct ...

On the basis of the appearance of sections of the mass stained with hematoxylin and eosin, we made a diagnosis of a spindle cell tumor (Fig. 2). Such tumors are a highly heterogeneous group that ...

A cystic neoplasm needs to be considered when a patient presents ... The submucosal layer consists of a highly cellular stroma of spindle cells with elongated nuclei similar to the “ovarian stroma” ...