Multi-epitope immunopurifications of huntingtin (HTT) from vulnerable brain regions of Huntington’s disease (HD) models ...

DGIST Department of Brain Sciences Professor Lee Kwang and his team have discovered a new correlation between neural signaling in the brain and dopamine signaling in the striatum. The human brain ...

Behind this mechanism is dopamine released within the striatum, the largest structure of the subcortical basal ganglia, which links motor movements and motivation. Yet it has remained unclear ...

Huntington's disease is a rare genetic, autosomal dominant, neurodegenerative disease, caused by CAG repeat expansions in the HTT gene, that is polymorphic on the healthy allele and contains more than ...