Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells
More information: Saima Usman et al, A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer ...
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Mutant Vimentin Promotes Aggressive Breast Cancer Growth
Vimentin, a type III intermediate filament (IF) protein, is primarily expressed in mesenchymal cells, which give rise to connective tissue, blood vessels, and lymphatic tissue. Despite extensive ...