A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G ...

A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs).

Several drugs have been introduced for psychiatric ... to be a potent antagonist of the metabotropic glutamate receptor mGluR5 — a target unknown at the time of this compound's discovery 31.

That would be an important advance to complement ongoing work Bear's lab has done to correct fragile X protein synthesis levels via another receptor called mGluR5. In the new study, Bear and ...