Crown BioScience experts explore organoid models and high-content imaging to evaluate T-cell-targeted therapies and ...

Both studies, which are reporting the results of early-stage clinical trials, show that the interventions were safe, and that ...

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how ...

Even in the case of uncomplicated infections, the body prepares itself early on for the possibility of a more severe course.

Physician-scientists at Memorial Sloan Kettering Cancer Center (MSK) recently published two papers that advance the science of addressing critical issues with CAR T cell therapy in patients with ...

Even in the case of uncomplicated infections, the body prepares itself early on for the possibility of a more severe course. A research team has now uncovered this mechanism. The scientists showed ...

image: QRICH1 fine-tunes the signaling of T cell receptors by regulating CARD11 view more Credit: Nicole M. Carter In a study ...

A team of researchers has successfully created more effective immune cells that can fight cancer without damaging healthy ...

A bold funding initiative aims to help scientists predict a T cell’s target antigens, with implications far beyond cancer therapy.

CAR T-cell therapy has significantly improved outcomes for B-ALL patients, but relapse still occurs in over 50% of cases, leaving many with limited treatment options. Ongoing research aims to ...

The cells were also found to require the proteins Retinoic Acid-Related Orphan Receptor-gamma-t (RORγt) and PR domain-containing 16 (Prdm16) to effectively protect tolerated proteins from the ...