Malfunctioning of the enzyme CDK7 is crucial to many cancers, making drugs that target it a high priority. Despite some ...

Zentalis Pharmaceuticals, Inc.’s ZNTL share price has dipped by 8.97%, which has investors questioning if this is right time ...

Events across the Metroplex have been canceled or delayed as hail and strong winds are expected Saturday morning.

Relay Therapeutics, Inc.’s RLAY share price has dipped by 12.66%, which has investors questioning if this is right time to ...

The interplay between aging and cellular senescence reveals insights into chronic inflammation and potential strategies for enhancing healthspan and longevity.

Revolution Medicines, Inc. (Nasdaq: RVMD), a late-stage clinical oncology company developing targeted therapies for patients ...

Circle Pharma, a clinical-stage biopharmaceutical company focused on developing cell-permeable macrocycle therapeutics, today announced that Chief Executive Officer David Earp, JD, Ph.D., will present ...

Notably, Cyclin D1 protein plays a crucial role in miR-146b-induced BCa cell proliferation, as confirmed by Western blotting (p < 0.05), with each experiment performed in triplicate. Mechanistic ...

Positive azenosertib clinical data demonstrated clinically meaningful results in patients with Cyclin E1+ platinum-resistant ovarian cancer ...

Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.

For decades, cancer researchers and pharmaceutical companies have eyed cyclin dependent kinase (CDK7) with interest due to its role as a "master regulator" of cell proliferation. CDK7 does this in two ...

García-Vázquez et al. identify GTSE1 as a novel target of the cyclin D1-CDK4/6 kinases. The authors show that GTSE1 is phosphorylated at four distinct serine residues and that this phosphorylation ...