News

Frontiers21d
New use of an old drug: mechanism of oseltamivir phosphate inhibiting liver cancer through regulation of lipophagy via NEU1
Subsequent experiments demonstrated that NEU1 knockdown reduced lipid accumulation through promoting perilipin 2 (PLIN2)-mediated lipophagy. Notably, OP (NEU1 inhibitor), promoted lipophagy, thereby ...
eLife1mon
Single-nucleus transcriptomics reveal the cytological mechanism of conjugated linoleic acids in regulating intramuscular fat deposition
College of Animal Sciences, Zhejiang University, Hangzhou, China Key Laboratory of Molecular Animal Nutrition (Zhejiang University), Ministry of Education, Hangzhou, China Key Laboratory of Animal ...
ki.se1y
Autophagy and cardiovascular disease – Team Ewa Ehrenborg
The research is about cardiovascular disease, which is a leading cause of morbidity and mortality worldwide. The main culprit is atherosclerosis, which is characterized by accumulation of lipids and ...
ki.se1y
Heart failure with reduced and preserved ejection fraction. Clinical and translational aspects. – Research group Lars Lund
Heart failure is associated with poor quality of life, is the most common cause of hospitalization, and is associated with high mortality and high costs to society. Heart failure is associated with ...
eLife3y
Exceptional stability of a perilipin on lipid droplets depends on its polar residues, suggesting multimeric assembly
We analyze the stability of perilipin AHs on the lipid surface and their ability to form an immobile structure using various cellular and biochemical approaches, as well as a novel microfluidics ...